Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression. Biological Psychiatry

Ja Wook Koo, Dipesh Chaudhury, Ming-Hu Han and Eric Nestler (2019), DOI: 10.1016

A key noradrenergic brainstem-mesolimbic circuit: promotion of resilience to social stress. Chronic Stress

Hongxing Zhang, Dipesh Chaudhury, Sarah Montgomery, Jun-Li Cao and Ming-Hu (2019). Chronic Stress (Commentary)

The role of dopamine in aversively motivated behavior.

Basma Radwan, He Liu and Dipesh Chaudhury (2019). Volume 1713 of Brain Research (BRES). 


The role of dopamine in mood disorders and the associated changes in circadian rhythms and sleep-wake cycle.

Basma Radwan, He Liu and Dipesh Chaudhury (2018). Brain Research, 18: 30597

Modeling of inhomogeneous electromagnetic field in the nervous system: a novel paradigm in understanding cell interactions, disease etiology and therapy. 

Isakovic J, Dobbs-Dixon I, Dipesh Chaudhury and Mitrecic D (2018). Scientific Reports, 8; 12909.

Alpha1 and beta3 adrenergic receptor-mediated mesolimbic homeostatic plasticity confers resilience to social stress in susceptible mice.

Hongxing Zhang, Dipesh Chaudhury, Alexander R. Nectow, Allyson K. Friedman, Song Zhang, Barbara Juarez, He Liu, Madeline L. Pfau, Hossein Aleyasin, Cheng Jiang, Marshall Crumiller, Erin S. Calipari, Stacy M. Ku, Carole Morel, Nikos Tzavaras, Sarah E. Montgomery, Michelle He, Stephen R. Salton, Scott J. Russo, Eric J. Nestler, Jeffrey M. Friedman, Jun-Li Cao, and Ming-Hu Han. (2018). Biological Psychiatry, 18; 31818.


Midbrain circuit regulation of individual alcohol drinking behaviors in mice. 

Barbara Juarez, Carole Morel, Stacy M. Ku, Yutong Liu, Hongxing Zhang, Sarah Montgomery, Hilledna Gregoire, Efrain Ribeiro, Marshall Crumiller, Ciorana Roman-Ortiz, Jessica J. Walsh, Kelcy Jackson, Denise E. Croote, Yingbo Zhu, Song Zhang, Leandro F. Vendruscolo, Scott Edwards, Amanda Roberts, Georgia E. Hodes, Yongke Lu, Erin S. Calipari, Dipesh Chaudhury, Allyson K. Friedman & Ming-Hu Han (2017). Nat. Communications, December 20; 8(1):2220 [A, E, I]


Understanding Mood Disorders Using Electrophysiology and Circuit Breaking.

He Liu and Dipesh Chaudhury. In Book: Decoding Neural Circuit Structure and Function: Cellular Dissection Using Genetic Model Organisms.Chapter 14, Page 343-370. (Book Chapter - Springer International Publication) Editors: Arzu Celik and Mathias F. Wernet, 2017



Regulation and modulation of depression-related behaviours: Role of dopaminergic neurons.

Basma Radwan, He Liu and Dipesh Chaudhury. Dopamine and Sleep (Book Chapter-Springer) Editors: Jaime Monti, SR Pandi-Perumal and S. Chokroverty, 2016

Basal forebrain projections to the lateral habenula modulate aggression reward

Sam A. Golden, Mitra Heshmati1, Meghan Flanigan, Dan J. Christoffel, Kevin Guise, Madeline L. Pfau, Hossein Aleyasin, Caroline Menard, Hongxing Zhang, Georgia E. Hodes, Dana Bregman, Lena Khibnik, Jonathan Tai, Nicole Rebusi, Brian Krawitz, Dipesh Chaudhury, Jessica J. Walsh, Ming-Hu Han, Matt L. Shapiro & Scott J. Russo. Nature, 2016


KCNQ channel openers reverse depressive symptoms via an active resilience mechanism

Allyson Friedman, Barbara Juarez, Stacy Ku, Hongxing Zhang, Jessica Walsh, Dipesh Chaudhury, Angel Hawkins, Song Zhang, Rhodora Calizo, David Dietz, James Murrough, Maria Ribadeneira, Erik Wong, Rachael Neve and Ming-Hu Han. Nat. Communtion, 2016



Neuronal Correlates of Depression

Dipesh Chaudhury, He Liu, Ming-Hu Han. Cellular and Molecular Life Science. 72: 4681-4920. 2015

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer J, Deisseroth K, Han MH, Nestler EJ. Nat Commun. 8: 8062. 2015



Optogenetics: Illuminating the neural basis of rodent behavior

Francis TC, Chaudhury D, Lobo MK. Open Access Animal Physiology. 6:33-51. (2014)

Loss of BDNF Signaling in D1R-Expressing NAc Neurons Enhances Morphine Reward by Reducing GABA Inhibition

Koo JW, Lobo MK, Chaudhury D, Labonté B, Friedman A, Heller E, Peña CJ, Han MH, Nestler EJ. Neuropsychopharmacology. 2014 Oct;39(11):2646-53.

Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience

Friedman AK, Walsh JJ, Juarez B, Ku SM, Chaudhury D, Wang J, Li X, Dietz DM, Pan N, Vialou VF, Neve RL, Yue Z, Han MH. Science, 2014 Apr 18;344(6181):313-9

Cocaine-mediated reduction of G9a activity promotes a striatopallidal to striatonigral ‘switching’ phenotype and enhanced drug sensitivity

Ian Maze, Dipesh Chaudhury, David M. Dietz, Melanie Von Schimmelmann, Mary K. Lobo, Rosemary C. Bagot, Pamela J. Kennedy, HaoSheng Sun, Gustavo Turecki, Alexander Tarakhovsky, Paul Greengard, Ming-Hu Han, Anne Schaefer and Eric J. Nestler . Nature Neuroscience 2014



Stress gates neural activation of BDNF in the mesolimbic reward pathway.

Jessica J. Walsh, Allyson K. Friedman, Haosheng Sun, Elizabeth A. Heller, Stacy M. Ku, Barbara Juarez, Veronica L. Burnham, Michelle S. Mazei-Robison, Deveroux Ferguson, Sam A. Golden, Ja Wook Koo, Dipesh Chaudhury, Daniel J. Christoffel, Lisa Pomeranz, Jeffrey M. Friedman, Scott J. Russo, Eric J. Nestler & Ming-Hu Han. Nature Neuroscience, 2013

Delta-FosB Induction in Striatal Medium Spiny Neuron Subtypes in Response to Chronic Pharmacological, Emotional, and Optogenetic Stimuli.

Mary Kay Lobo, Samir Zaman, Diane Damez Werno, Ja Wook Koo, Rosemary Bagot, Jennifer DiNieri, Alexandria Nugent, Eric Finkel, Dipesh Chaudhury, Ramesh Chandra, Efrain Riberio, Jacqui Rabkin, Ezekiell Mouzon, Roger Cachope, Joseph Cheer, Ming-Hu Han, David Dietz, David Self, Yasmin Hurd, Vincent Vialou, and Eric Nestler. The Journal of Neuroscience, 2013

Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine cytoskeleton regulator Tiam1

Ramesh Chandra, Jeffrey Lenz, Amy M. Gancarz, Dipesh Chaudhury, Gabrielle L. Schroeder, Ming-Hu Han, Joseph F. Cheer, David M. Dietz, Mary Kay Lobo. Frontiers In Neuroscience, 2013

Class i hdac inhibition blocks cocaine-induced plasticity through targeted changes in histone methylation

Pamela J. Kennedy, Jian Feng, A.J. Robison, Ian Maze, Ana Badimon, Ezekiell Mouzon, Dipesh Chaudhury, Diane M. Damez-Werno, Stephen J. Haggarty, Ming-Hu Han, Rhonda Bassel-Duby, Eric N. Olson & Eric J. Nestler. Nature Neuroscience, 2013; doi:10.1038/nn.3354


Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, Lobo MK, Neve RL, Friedman JM, Russo SJ, Deisseroth K, Nestler EJ, Han MH. Nature, 2013 Jan 24; 493(7433):532-6



BDNF is a negative modulator of morphine action

Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, Lobo MK, Neve RL, Russo SJ, Han MH, Nestler EJ. Science, 2012 Oct 5; 338(6103):124-8


Odor fear conditioning modifies piriform cortex local field potentials both during conditioning and during post-conditioning sleep

Barnes DC, Chapuis J, Chaudhury D, Wilson DA. PLoS One, 2011 Mar 23; 6(3):e18130



Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

Lobo MK, Covington HE 3rd, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, Nestler EJ. Science, 2010 Oct 15; 330(6002):385-90.


Olfactory bulb habituation to odor stimuli

Dipesh Chaudhury, Laura Manella, Adolfo Arellanos, Olga Escanilla, Thomas A. Cleland and Christiane Linster. Behavioral Neuroscience, 2010; 124 (4) 490-499



Bulbar acetylcholine enhances neural and perceptual odor discrimination

Dipesh Chaudhury, Olga Escanilla, and Christiane Linster. The Journal of Neuroscience, January 7, 2009; 29(1):52– 60



Select cognitive deficits in vasoactive intestinal peptide deficient mice

Dipesh Chaudhury, Dawn H Loh, Joanna M Dragich, Arkady Hagopian and Christopher S Colwell. BMC Neuroscience, 2008; 9:63



Melatonin inhibits hippocampal long term potentiation

Louisa M. Wang, Nanthia A. Suthana, Dipesh Chaudhury, David R. Weaver, and Christopher S. Colwell. European Journal of Neuroscience, 2005; 22, 2231-2237


Circadian regulation of hippocampal long-term potentiation

Chaudhury, D., Wang, LW and Colwell, CS. Journal of Biological Rhythms, 2005; 20, 225-236



Circadian modulation of learning and memory in fear-conditioned mice

Chaudhury, D., and Colwell, CS. Behavioural Brain Research, 2002; 133, 95-108


Passive avoidance training results in increased responsiveness of voltage and ligand-gated channels in chick synaptoneurosomes

Salinska, E.J., Chaudhury, D., Bourne, R.C. and Rose, S.P.R. Neuroscience, 1999; 93(4):1507-14